Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Nitrobenzaldehyde | HCID 11101 | — |
| Reactant | 5-(3,4-dichlorophenyl)cyclohexane-1,3-dione | HCID 599126 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 10250916 | HCID 10250916 | — |
Reaction Steps
A mixture of 3.25 g of 2-nitrobenzaldehyde and 5.5 g of 5-(3,4-dichlorophenyl)-1,3-cyclohexanedione in 20 ml of glacial acetic acid and 20 ml of concentrated hydrochloric acid is heated at 80° C. for 0.5 hr, cooled and poured into 300 ml of water. The solid is digested in hot methanol and dried in vacuo to give 7-chloro-3-(3,4-dichlorophenyl)-3,4-dihydro-10-hydroxy-1,9(2H,-10H)-acridinedione; mp 268°-269° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04291034 |
|---|
| Source dataset | uspto-grants-1981_09 |
|---|
| ORD ID | ord-9e1b0b4ee0a84ea0ad4ecc1a5bbf527a |
|---|
| Source note | uspto-grants-1981_09 |
|---|
