N,N-Dimethyl-1,3-propanediamine → HCID 547232, compound

HRID 1578084Notes

Reaction equation

HRID 1578084 reaction equation
[Cl:1][C:2]1[CH:15]=[C:14]2[C:5]([NH:6][C:7]3[CH2:8][CH:9]([C:18]4[CH:23]=[CH:22][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:20][CH:19]=4)[CH2:10][C:11](=O)[C:12]=3[C:13]2=[O:16])=[CH:4][CH:3]=1.[CH3:28][N:29]([CH3:34])[CH2:30][CH2:31][CH2:32][NH2:33]>>[Cl:1][C:2]1[CH:15]=[C:14]2[C:5]([NH:6][C:7]3[CH2:8][CH:9]([C:18]4[CH:19]=[CH:20][C:21]([C:24]([F:26])([F:27])[F:25])=[CH:22][CH:23]=4)[CH2:10][C:11](=[N:33][CH2:32][CH2:31][CH2:30][N:29]([CH3:34])[CH3:28])[C:12]=3[C:13]2=[O:16])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 10340441HCID 10340441, compound

Product 1

HCID 547232HCID 547232, compound

Procedure

By following the above procedure and using 7-chloro3-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1,9(2H,10H)acridinedione instead of 7-chloro-3-(3,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione and N,N-dimethyl-1,3-propanediamine instead of N,N-diethylenediamine one obtains 7-chloro-1-[[3-(dimethylamino)propyl]imino]-1,3,4,10-tetrahydro-3-[4-(trifluoromethyl)phenyl]-9(2H)-acridinone; mp 211°-213° C. after recrystallization from ethanol.

Sources & evidence

ORD record
ord-f877cb245f2549e596800b5f01399f12
Source dataset
uspto-grants-1981_09
Patent number
US04291034

Reaction notes

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