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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1578133Generated: November 4, 2026

Ammonia → 4-hydroxy-4-[(4-methyl)phenyl]-1-(4-mercapto-1-oxobutyl)-L-proline

https://huagongshe.com/reaction/1578133

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant1-[4-(Acetylthio)-1-oxobutyl]-4-hydroxy-4-[(4-methyl)phenyl]-L-prolineHCID 22817492—
Product4-hydroxy-4-[(4-methyl)phenyl]-1-(4-mercapto-1-oxobutyl)-L-prolineHCID 22817579—

Reaction Steps

The product from part (b) is treated with concentrated ammonia according to the procedure of Example 2 to yield 4-hydroxy-4-[(4-methyl)phenyl]-1-(4-mercapto-1-oxobutyl)-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04291040
Source datasetuspto-grants-1981_09
ORD IDord-8ccc13d3453c4f0fb5bdb9de2871ded1
Source noteuspto-grants-1981_09