Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 6,7-Dichloro-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 12733886 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 13354170 | HCID 13354170 | — |
Reaction Steps
A mixture of 6,7-dichloro-1-ethyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (4.3 g), pyrrolidine (10 cm3) and DMSO (45 cm3) was heated for 2 hours at 110° C. Part of the reaction product precipitated during the reaction. After cooling, it was filtered off and recrystallised from DMF (50 cm3). 3 g of 6-chloro-1-ethyl-4-oxo-7-pyrrolidino-1,4-dihydro-quinoline-3-carboxylic acid, m.p. 325° C., were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04292317 |
|---|
| Source dataset | uspto-grants-1981_09 |
|---|
| ORD ID | ord-325c3fc514ea4eaf8db25871fd690130 |
|---|
| Source note | uspto-grants-1981_09 |
|---|
