Acetic Acid → HCID 178445997, compound

Participants

Reaction Steps

20 g of carbobenzoxyglycyl-L-histidyl-L-leucine methyl ester is added to 100 ml of 25% HBr solution in acetic acid and this mixture is stirred for one hour to split off the carbobenzoxy group, and then 2000 ml of absolute ether is added. The precipitate thus produced is filtered off and washed with ethyl ether and dried in a desiccator.

Provenance & Evidence