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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 157833Generated: October 26, 2026

3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid → 3'-Chloro-4'-[2-(1-ethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-3-fluoro-biphenyl-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/157833

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-(methoxycarbonyl)benzeneboronic acidHCID 2782818—
Reactant5-[2-(4-Bromo-2-chloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1-ethyl-1H-pyridin-2-oneHCID 57421323—
Product3'-Chloro-4'-[2-(1-ethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-3-fluoro-biphenyl-4-carboxylic acid methyl esterHCID 66782741—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-71ea9715fc794737ba3986ee76b57017
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)