Phosphorus pentachloride → HCID 54434434, compound

HRID 1578365Notes

Reaction equation

HRID 1578365 reaction equation
[Cl:1][CH:2]([Cl:16])[C:3]([O:5][N:6]=[C:7]([C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:8](O)=[O:9])=[O:4].P(Cl)(Cl)(Cl)(Cl)[Cl:18]>C(Cl)Cl>[Cl:1][CH:2]([Cl:16])[C:3]([O:5][N:6]=[C:7]([C:11]1[O:12][CH:13]=[CH:14][CH:15]=1)[C:8]([Cl:18])=[O:9])=[O:4]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 53711305HCID 53711305, compound

Product 1

HCID 54434434HCID 54434434, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

To an ice-cold stirred suspension of 2-dichloroacetoxyimino-2-(fur-2yl)acetic acid (1.5 g) in dry methylene chloride (70 mls) was added dropwise a freshly prepared solution of phosphorus pentachloride (1.0 equiv.) in methylene chloride. When solution was complete the solvent was evaporated at low temperature and the residual oil azeotroped with benzene to give 2-dichloroacetoxyimino-2(fur-2yl)acetyl chloride (syn-isomer) as a pale yellow oil which was used directly.

Workup

  1. customwas evaporated at low temperature
  2. customthe residual oil azeotroped with benzene

Sources & evidence

ORD record
ord-0294a363f76e41ed89c4ba14dd733c97
Source dataset
uspto-grants-1976_02
Patent number
US03936443

Reaction notes

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