反应详情

A mixture of 2.68 g. of 1-acetyl-3-(2-bromoethyl)-indoline, 2.00 g. of 4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride and 4.00 g. of sodium bicarbonate in 40 ml. of sec-butyl alcohol is stirred at reflux temperature for 18 hours. The cooled mixture is filtered, and the filtrate is evaporated. The residue is dissolved in acetone and the addition of water gives white crystals, m.p. 109°-111°C.

1. additionA mixture of 2.68 g
2. temperatureat reflux temperature for 18 hours
3. filtrationThe cooled mixture is filtered
4. customthe filtrate is evaporated
5. dissolutionThe residue is dissolved in acetone
6. additionthe addition of water
7. customgives white crystals, m.p. 109°-111°C.