1,2,3,6-Tetrahydro-4-phenylpyridine → HCID 21559978, compound

HRID 1578408Notes

Reaction equation

HRID 1578408 reaction equation
[C:1]([N:4]1[C:12]2[CH:11]=[C:10]3[O:13][CH2:14][O:15][C:9]3=[CH:8][C:7]=2[CH:6]([CH2:16][CH2:17]Br)[CH2:5]1)(=[O:3])[CH3:2].[C:19]1([C:25]2[CH2:26][CH2:27][NH:28][CH2:29][CH:30]=2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[C:1]([N:4]1[C:12]2[CH:11]=[C:10]3[O:13][CH2:14][O:15][C:9]3=[CH:8][C:7]=2[CH:6]([CH2:16][CH2:17][N:28]2[CH2:27][CH:26]=[C:25]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:30][CH2:29]2)[CH2:5]1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 825531,2,3,6-Tetrahydro-4-phenylpyridineHCID 21559973HCID 21559973, compound

Product 1

HCID 21559978HCID 21559978, compound

Procedure

In the manner described in Example 1, treatment of 5-acetyl-7-(2-bromoethyl)-6,7-dihydro-5H-1,3-dioxolo[4,5-f]-indole with 1,2,3,6-tetrahydro-4-phenylpyridine gives white crystals, m.p. 90°-91°C., after recrystallization from dilute acetone.

Workup

  1. customgives white crystals, m.p. 90°-91°C.
  2. customafter recrystallization from dilute acetone

Sources & evidence

ORD record
ord-364f9cf2efbe444dbd4afad4363b7127
Source dataset
uspto-grants-1976_02
Patent number
US03936464

Reaction notes

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