HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidine → HCID 21559958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | 4-(4-Chlorophenyl)piperidine | HCID 1203613 | — |
| Reactant | Pyridine, 1,2,3,6-tetrahydro-4-[4-(trifluoromethyl)phenyl]- | HCID 12440708 | — |
| Reactant | HCID 21559977 | HCID 21559977 | — |
| Product | HCID 21559958 | HCID 21559958 | — |
| Product | HCID 21559976 | HCID 21559976 | — |
| Product | HCID 54020821 | HCID 54020821 | — |
Reaction Steps
In the manner described in Example 1, reaction of 5-propionyl-6-methyl-6,7-dihydro-7-(2-bromoethyl)-5H-1,3-dioxolo[4,5-f]indole with 4-phenylpiperidine, 4-(p-chlorophenyl)piperidine, or 1,2,3,6-tetrahydro-4-(α,α,α-trifluoro-p-tolyl)pyridine provides the corresponding 5-propionyl-6-methyl-6,7-dihydro-7-[2-(4-phenylpiperidino) ethyl]-5H-1,3-dioxolo[4,5-f]indole, 5-propionyl-6-methyl-6,7-dihydro-7-{2-[4(p-chlorophenyl)piperidino]ethyl}-5H-1,3-dioxolo-[4,5-f]-indole, and 5-propionyl-6-methyl-6,7-dihydro-7-{2-[3,6-dihydro-(α,α,α-trifluoro-p-tolyl)-1(2H)-pyridyl]ethyl}-5H-1,3-dioxolo[4,5-f]indole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03936464 |
| Source dataset | uspto-grants-1976_02 |
| ORD ID | ord-04261106b6794e838c10000248fcb3a0 |
| Source note | uspto-grants-1976_02 |