HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3,6-Tetrahydro-4-phenylpyridine → HCID 21559968, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3,6-Tetrahydro-4-phenylpyridine | HCID 82553 | — |
| Reactant | 4-(4-Chlorophenyl)-1,2,3,6-tetrahydropyridine | HCID 185717 | — |
| Reactant | 4-(4-(Trifluoromethyl)phenyl)piperidine | HCID 12440702 | — |
| Reactant | HCID 21559966 | HCID 21559966 | — |
| Product | HCID 21559968 | HCID 21559968 | — |
| Product | HCID 54385492 | HCID 54385492 | — |
| Product | HCID 54504784 | HCID 54504784 | — |
Reaction Steps
In the manner described in Example 5, reaction of 1-isobutyryl-2-ethyl-3-(2-bromoethyl)-5-ethoxyindoline with 4-phenyl-1,2,3,6-tetrahydropyridine, 4-(p-chlorophenyl)-1,2,3,6-tetrahydropyridine, or 4-(p-trifluoromethylphenyl)piperidine provides the corresponding 1-isobutyryl-2-ethyl-5-ethoxy-3-[2-(4-phenyl-3,6-dihydro-1(2H)-pyridyl)ethyl]indoline, 1-isobutyryl-2-ethyl-5-ethoxy-3-{2-[4-(p-chlorophenyl)-3,6-dihydro-1(2H)-pyridyl]ethyl} indoline, and 1-isobutyryl-2-ethyl-5-ethoxy-3-{2-[4-(p-trifluoromethylphenyl)piperidino]-ethyl} indoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03936464 |
| Source dataset | uspto-grants-1976_02 |
| ORD ID | ord-411eb220951a4e509b51ad52de532eaa |
| Source note | uspto-grants-1976_02 |