HCID 21559968, compound → HCID 21559967, compound

HRID 1578415Notes

Reaction equation

HRID 1578415 reaction equation
[C:1]([N:6]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH2:16][CH3:17])=[CH:12][CH:13]=2)[CH:8]([CH2:18][CH2:19][N:20]2[CH2:25][CH:24]=[C:23]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[CH2:22][CH2:21]2)[CH:7]1[CH2:32][CH3:33])(=[O:5])[CH:2]([CH3:4])[CH3:3].[C:34]([N:39]1[C:47]2[C:42](=[CH:43][C:44]([O:48][CH2:49][CH3:50])=[CH:45][CH:46]=2)[CH:41]([CH2:51][CH2:52][N:53]2[CH2:58][CH:57]=[C:56]([C:59]3[CH:64]=[CH:63][C:62]([Cl:65])=[CH:61][CH:60]=3)[CH2:55][CH2:54]2)[CH:40]1[CH2:66][CH3:67])(=[O:38])[CH:35]([CH3:37])[CH3:36]>>[C:1]([N:6]1[C:14]2[C:9](=[CH:10][C:11]([O:15][CH2:16][CH3:17])=[CH:12][CH:13]=2)[CH:8]([CH2:18][CH2:19][N:20]2[CH2:25][CH2:24][CH:23]([C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)[CH2:22][CH2:21]2)[CH:7]1[CH2:32][CH3:33])(=[O:5])[CH:2]([CH3:3])[CH3:4].[C:34]([N:39]1[C:47]2[C:42](=[CH:43][C:44]([O:48][CH2:49][CH3:50])=[CH:45][CH:46]=2)[CH:41]([CH2:51][CH2:52][N:53]2[CH2:58][CH2:57][CH:56]([C:59]3[CH:64]=[CH:63][C:62]([Cl:65])=[CH:61][CH:60]=3)[CH2:55][CH2:54]2)[CH:40]1[CH2:66][CH3:67])(=[O:38])[CH:35]([CH3:36])[CH3:37]

Participants

4

Reactant 2

HCID 21559968HCID 21559968, compoundHCID 54385492HCID 54385492, compound

Product 2

HCID 21559967HCID 21559967, compoundHCID 54196555HCID 54196555, compound

Procedure

In the manner described in Example 14, reduction of 1-isobutyryl-2-ethyl-5-ethoxy-3-[2-(4-phenyl-3,6-dihydro-1(2H)-pyridyl)ethyl]indoline and 1-isobutyryl-2-ethyl-5-ethoxy-3-{2-[4-(p-chlorophenyl)-3,6-dihydro-1(2H)-pyridyl]-ethyl} indoline provides the corresponding 1-isobutyryl-2-ethyl-5-ethoxy-3-[2-(4-phenylpiperidino)ethyl]indoline and 1-isobutyryl-2-ethyl-5-ethoxy-3-{2-[4-(p-chlorophenyl)piperidino]ethyl} indoline.

Sources & evidence

ORD record
ord-8cea8895921240eab7438f3930670a58
Source dataset
uspto-grants-1976_02
Patent number
US03936464

Reaction notes

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