HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 20332624, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 1-Phenyl-1,2-ethanediol | HCID 7149 | — |
| Reactant | 2-Bromo-1-(2,4-dichlorophenyl)ethan-1-one | HCID 75828 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20332624 | HCID 20332624 | — |
Reaction Steps
A mixture of 13.4 parts of 2-bromo-2',4'-dichloroacetophenone, 8.4 parts of α-(hydroxymethyl)benzyl alcohol, 1.15 parts of p-toluenesulfonic acid, 160 parts of benzene and 140 parts of n-butanol is stirred and refluxed for 48 hours with a water-separator. The solvent is removed in vacuo. The residue is purified by column-chromatography over silica gel, using chloroform as eluent. The pure fractions are collected and the eluent is evaporated, yielding 2-(bromomethyl)-2-(2,4-dichlorophenyl)-4-phenyl-1,3-dioxolane as residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03936470 |
| Source dataset | uspto-grants-1976_02 |
| ORD ID | ord-c2ff1e09a405494aa5621576f1499022 |
| Source note | uspto-grants-1976_02 |