Acetic Anhydride → HCID 54323834, compound

HRID 1578496Notes

Reaction equation

HRID 1578496 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]([CH3:15])[N:8]=[C:7]([S:16]([CH3:18])=O)[C:6]2=[O:19].[C:20]([O:23]C(=O)C)(=[O:22])[CH3:21]>>[C:20]([O:23][CH2:18][S:16][C:7]1[C:6](=[O:19])[C:5]2[C:10](=[CH:11][C:12]([O:13][CH3:14])=[C:3]([O:2][CH3:1])[CH:4]=2)[N:9]([CH3:15])[N:8]=1)(=[O:22])[CH3:21]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 21559127HCID 21559127, compound

Product 1

HCID 54323834HCID 54323834, compound

Procedure

A mixture of 11 g of 6,7-dimethoxy-1-methyl-3-(methylsulfinyl)-4(1H)-cinnolinone and 100 ml of acetic anhydride was refluxed for 2 hours. The solution was chilled, and the crystalline precipitate was filtered off, washed with Skelly B, and recrystallized from CH3CN, mp. 229°-33°, yield 11 g (87%).

Workup

  1. temperaturewas refluxed for 2 hours
  2. temperatureThe solution was chilled
  3. filtrationthe crystalline precipitate was filtered off
  4. washwashed with Skelly B
  5. customrecrystallized from CH3CN, mp. 229°-33°, yield 11 g (87%)

Sources & evidence

ORD record
ord-d8252f7536aa4314a58dca7dec4bfe06
Source dataset
uspto-grants-1976_02
Patent number
US03937704

Reaction notes

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