Methyl iodide → HCID 131710022, compound

HRID 1578547Notes

Reaction equation

HRID 1578547 reaction equation
[C:1]1([C:7]([CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[OH:10])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17]1(OC2C=CC=CC=2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[OH-].[Na+].[CH3:32]I>CS(C)=O>[C:17]1([O:8][C:7]([CH3:32])([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:9](=[O:10])[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 14798Sodium HydroxideHCID 21868088HCID 21868088, compound

Product 1

HCID 131710022HCID 131710022, compoundYield 82.9%

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

18 g benzoin-phenyl ether are reacted in 200 ml DMSO with 25 g of a 10% by weight aqueous sodium hydroxide solution and 11.8 g methyl iodide at 20°C. After working up and filtering through silica gel/benzene, there are obtained, besides 6.2 g of educt, 11.8 g α-methyl-benzoin phenyl ether of m.p. 91.5°C (ethanol).

Workup

  1. filtrationfiltering through silica gel/benzene, there

Sources & evidence

ORD record
ord-df76171319774079a69cd0635183979b
Source dataset
uspto-grants-1976_02
Patent number
US03937722

Reaction notes

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