Water → HCID 21559721, compound

HRID 1578612Notes

Reaction equation

HRID 1578612 reaction equation
[C:1]([C:4]1[C:9](=[O:10])[C:8]2[CH:11]=[CH:12][C:13]([OH:15])=[CH:14][C:7]=2[O:6][C:5]=1[C:16]([O:18]CC)=[O:17])(=[O:3])N.[OH2:21]>S(=O)(=O)(O)O>[OH:15][C:13]1[CH:12]=[CH:11][C:8]2[C:9](=[O:10])[C:4]([C:1]([OH:3])=[O:21])=[C:5]([C:16]([OH:18])=[O:17])[O:6][C:7]=2[CH:14]=1

Participants

4

Reactant 2

HCID 962WaterHCID 21559729HCID 21559729, compound

Product 1

HCID 21559721HCID 21559721, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

A mixture of 2.0 g (7.2 mmol) of ethyl 3-carbamoyl-7-hydroxy-4-oxo-4H-1-benzopyran-2-carboxylate in 10 ml of 80% sulfuric acid was heated over a steam bath for 1 hr. and then poured into 50 ml of water. This was filtered and the filtrate evaporated in vacuo. The gummy residue was triturated with a minimum amount of water, the solid filtered and dried, mp 255°-257°C.

Workup

  1. temperaturewas heated over a steam bath for 1 hr
  2. filtrationThis was filtered
  3. customthe filtrate evaporated in vacuo
  4. customThe gummy residue was triturated with a minimum amount of water
  5. filtrationthe solid filtered
  6. customdried

Sources & evidence

ORD record
ord-55f09baa6bf643de9917b40eb30a8f8a
Source dataset
uspto-grants-1976_02
Patent number
US03937837

Reaction notes

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