Pyridine → HCID 21559719, compound

HRID 1578613Notes

Reaction equation

HRID 1578613 reaction equation
[OH:1][C:2]1[CH:12]=[C:11]([OH:13])[CH:10]=[CH:9][C:3]=1[C:4]([CH2:6][C:7]#[N:8])=[O:5].[C:14](OC(=O)C)(=[O:16])[CH3:15].N1C=CC=[CH:23][CH:22]=1>>[C:14]([O:13][C:11]1[CH:10]=[CH:9][C:3]2[C:4](=[O:5])[C:6]([C:7]#[N:8])=[C:22]([CH3:23])[O:1][C:2]=2[CH:12]=1)(=[O:16])[CH3:15]

Participants

4

Reactant 3

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 21559725HCID 21559725, compound

Product 1

HCID 21559719HCID 21559719, compound

Procedure

A mixture of 5 g of 2,4-dihydroxybenzoyl acetonitrile, 15 ml of pyridine and 7.5 ml of acetic anhydride was left overnight at room temperature. The next morning the crystals were filtered and recrystallized from ethanol, mp 140°-141° C.

Workup

  1. filtrationThe next morning the crystals were filtered
  2. customrecrystallized from ethanol, mp 140°-141° C.

Sources & evidence

ORD record
ord-4499392b34e8488694fac6e93386266b
Source dataset
uspto-grants-1976_02
Patent number
US03937837

Reaction notes

Loading…