Sulfuric Acid → HCID 21559729, compound

HRID 1578618Notes

Reaction equation

HRID 1578618 reaction equation
[C:1]([C:3]1[C:8](=[O:9])[C:7]2[CH:10]=[CH:11][C:12]([OH:14])=[CH:13][C:6]=2[O:5][C:4]=1[C:15]([O:17][CH2:18][CH3:19])=[O:16])#[N:2].S(=O)(=O)(O)[OH:21]>>[C:1]([C:3]1[C:8](=[O:9])[C:7]2[CH:10]=[CH:11][C:12]([OH:14])=[CH:13][C:6]=2[O:5][C:4]=1[C:15]([O:17][CH2:18][CH3:19])=[O:16])(=[O:21])[NH2:2]

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 21559720HCID 21559720, compound

Product 1

HCID 21559729HCID 21559729, compound

Procedure

A mixture of 25.0 g (0.097 mol) of ethyl 3-cyano-7-hydroxy-4-oxo-4H-1-benzopyran-2-carboxylate in 230 ml conc. sulfuric acid was stirred at room temperature overnight. The mixture was then poured into 1.5 l of ice water with stirring. The resulting solid was filtered off, washed with water, and dried. 16.5 g (60%) mp > 320° C. from acetonitrile.

Workup

  1. stirringwith stirring
  2. filtrationThe resulting solid was filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-18c58bc0d74d44eda71b4fccce5f7354
Source dataset
uspto-grants-1976_02
Patent number
US03937837

Reaction notes

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