3-(Diethylamino)-1-propanol → Bis(3-diethylaminopropyl)dibenzothiophene-2,8-dicarboxylate dihydrochloride

Participants

Reaction Steps

A solution of 7.6 g (0.025 mole) of dibenzothiophene-2,8 -dicarbonyl chloride and 6.5 g (0.05 mole) of 3-diethylaminopropanol in 1 liter of chlorofrom is heated at reflux for two hours. The solution is concentrated to 500 ml, diluted with petroleum ether (75°-90°) and the precipitated solid is crystallized from methanol-isopropanol and finally from water-acetone to yield bis(3-diethylaminopropyl)dibenzothiophene-2,8-dicarboxylate dihydrochloride, M.P. 243°-245°C.

Provenance & Evidence