Potassium Iodide → HCID 68136329, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 32.6 g (0.08 mole) of 2,8-bis(4-chlorobutyryl)thioxanthene, 2 g of potassium iodide, 100 ml of diethylamine and 100 ml of tetrahydrofuran is heated for 24 hours with stirring in a Paar bomb at 110°C. Upon cooling, the mixture is evaporated to near dryness. The residue is dissolved in methylene chloride, washed with water then with saturated NaCl solution, dried over magnesium sulfate and filtered. The filtrate is evaporated to near dryness and recrystallized several times from methanol-diethyl ether and from acetone-methanol to give 2,8-bis(4-diethylaminobutyryl)thioxanthene dihydrochloride. M.P. 188°-191°C.

Provenance & Evidence