Water → HCID 21558484, compound

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Reaction Steps

A solution of 30 parts of dichlorosulphonylisocyanate in 100 parts of dry acetronitrile is slowly added dropwise to a suspension of 48.22 parts of 2,4-dichloro-6-phenylamino-s-triazine in 100 parts by volume of dry acetonitrile. The mixture is warmed gently and soon a clear, slightly yellowish solution forms. The reaction is brought to completion by subsequently stirring the solution for about 2 hours at 45°-50°C and then for 2 hours at room temperature. Then 320 parts by volume of water are added in such a manner that the temperature rises initially to 70°-75°C but is then immediately lowered. The precipitate which has formed is filtered off with suction, washed neutral with water and dried in vacuo to yield 52 parts of N-(2,4-dichloro-s-triazin-6-yl)-N-phenyl-urea which melts at 151°-154°C and is pure enough for most reactions. Recrystallisation from perchloroethylene yields a white, crystalline product which melts at 155°-157°C and has the following analytical values:

Provenance & Evidence