Chlorine → HCID 178430145, compound

HRID 1578689Notes

Reaction equation

HRID 1578689 reaction equation
[Cl:1]Cl.[NH2:3][C:4]1[N:13]=[C:12]([OH:14])[C:11]2[N:10]=[C:9]([CH3:15])[C:8]([CH3:17])([CH3:16])[NH:7][C:6]=2[N:5]=1.NC1N=C(O)C2N=C(CC)C(CCC)(CCC)NC=2N=1>C(O)(=O)C>[NH2:3][C:4]1[N:13]=[C:12]([OH:14])[C:11]2[N:10]=[C:9]([CH2:15][Cl:1])[C:8]([CH3:17])([CH3:16])[NH:7][C:6]=2[N:5]=1

Participants

5

Reactant 3

HCID 24526ChlorineHCID 178432362HCID 178432362, compoundHCID 178439210HCID 178439210, compound

Product 1

HCID 178430145HCID 178430145, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A slight exvess of chlorine was added with stirring to 2-amino-4-hydroxy-6-methyl-7,7-dimethyl-7,8-dihydropteridine, (II, X = Me, R1 =R2 =n-Pr) in glacial acetic acid, and the resulting precipitate was filtered off and washed with dry ether, and isolated analogously to the procedure described in Example 3.

Workup

  1. filtrationthe resulting precipitate was filtered off
  2. washwashed with dry ether
  3. customisolated analogously to the procedure

Sources & evidence

ORD record
ord-7ff190c0b3474c04b1696b69b28fae54
Source dataset
uspto-grants-1976_02
Patent number
US03939160

Reaction notes

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