Cyclopropylamine → 4-(Cyclopropylamino)-7-nitro-2,5-bis(trifluoromethyl)-benzimidazole

HRID 1578733Notes

Reaction equation

HRID 1578733 reaction equation
Cl[C:2]1[C:10]2[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=2[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=1[C:18]([F:21])([F:20])[F:19].[CH:22]1([NH2:25])[CH2:24][CH2:23]1>>[CH:22]1([NH:25][C:2]2[C:10]3[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=3[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=2[C:18]([F:21])([F:20])[F:19])[CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 1355549354-Chloro-7-nitro-2,5-bis(trifluoromethyl)benzimidazole

Product 1

HCID 1357839294-(Cyclopropylamino)-7-nitro-2,5-bis(trifluoromethyl)-benzimidazole

Procedure

4-Chloro-7-nitro-2,5-bis(trifluoromethyl)benzimidazole is reacted with cyclopropylamine to obtain the corresponding 4-(cyclopropylamino)-7-nitro-2,5-bis(trifluoromethyl)-benzimidazole, m.w., 354.2.

Sources & evidence

ORD record
ord-dfaf823c215d42e9b338481f4ca33440
Source dataset
uspto-grants-1976_02
Patent number
US03939166

Reaction notes

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