HCID 21558567, compound → HCID 135783924, compound
Reaction equation
Cl[C:2]1[C:10]2[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=2[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=1[C:18]#[N:19].[CH2:20]([CH:22]1[CH2:25][CH2:24][CH:23]1[NH2:26])[CH3:21]>>[CH2:20]([CH:22]1[CH2:25][CH2:24][CH:23]1[NH:26][C:2]1[C:10]2[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=2[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=1[C:18]#[N:19])[CH3:21]Participants
3
Procedure
4-Chloro-7-nitro-5-cyano-2-trifluoromethylbenzimidazole is reacted with 2-ethylcyclobutylamine to obtain 4-((2-ethylcyclobutyl)amino)-7-nitro-5-cyano-2-trifluoromethylbenzimidazole, m.w., 353.3.
Sources & evidence
- ORD record
- ord-10342660990749319bcd3e1dc6da544c
- Source dataset
- uspto-grants-1976_02
- Patent number
- US03939166
Reaction notes
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