HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 2-hydroxymethyl-5-nitro-N,N-dimethylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 6-Nitrophthalide | HCID 223584 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-hydroxymethyl-5-nitro-N,N-dimethylbenzamide | HCID 21423032 | — |
Reaction Steps
To a stirred solution of 6-nitrophthalide (2 g.) in ethanol (120 ml.) at room temperature was added dimethylamine (in ethanol 33.3% solution: 50 ml.). After stirring for 5 hours the solvent was evaporated off. The resulting gum was dissolved in ethyl acetate. On addition of petrol 60°-80° a white solid crystallised out.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03939180 |
| Source dataset | uspto-grants-1976_02 |
| ORD ID | ord-b0eba6d74e524bc8b149f9579fd5c4d3 |
| Source note | uspto-grants-1976_02 |