Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | HCID 21425190 | HCID 21425190 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 21425196 | HCID 21425196 | — |
Reaction Steps
A mixture of 1,3-bis-(p-methoxyphenyl)cyclobutane (13.57 g., 0.051 mole) and pyridine hydrochloride (46.8 g., 0.41 mole) is heated at 210°C. under a nitrogen atmosphere for 30 minutes and then poured into 500 ml. of water. Several ethyl acetate extracts are taken, combined, washed (dilute HCl, water), dried (MgSO4), and evaporated. The desired product after recrystallization from benzene weighs 8.1 g. (67%), m.p. 148°-163.5°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03939196 |
|---|
| Source dataset | uspto-grants-1976_02 |
|---|
| ORD ID | ord-87fe17db399d43fd85f821e4e15fed8f |
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| Source note | uspto-grants-1976_02 |
|---|
