HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 131710050, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Thiopheneacetyl chloride | HCID 162362 | — |
| Reactant | HCID 131710049 | HCID 131710049 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131710050 | HCID 131710050 | 46.6% |
Reaction Steps
The free base (XI) (80 mg) was treated with 2-thienylacetyl chloride (40 mg) and triethylamine (0.05 ml) in dry methylene chloride (5 ml) at -20°. After 15 minutes the solution was washed with brine, dried and evaporated. Chromatography on silica gave the cephem (X) (50 mg) which crystallised on trituration with dry ether. νmax (CHCl3) 3380, 1780, 1710, 1685 cm-1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03939157 |
| Source dataset | uspto-grants-1976_02 |
| ORD ID | ord-1dbc3cdffd60418ab0f355ed754a656e |
| Source note | uspto-grants-1976_02 |