HCID 131710054, compound → HCID 131710053, compound

Participants

Reaction Steps

The cephem ester (XX) (28 mg) was dissolved in trifluoroacetic acid (0.8 ml) and allowed to stand at room temperature for 30 min. The reaction mixture was evaporated azeotropically from dry benzene to give the acid (XXII) as a glass (25 mg) νmax (CHCl3) 1775, 1730-1750, 1675 cm-1The minimum inhibitory concentrations (MIC) of this compound against five typical Gram-positive bacteria are tabulated below:

Provenance & Evidence