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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15789Generated: October 25, 2026

Pivaloyl chloride → 2,2-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)propanamide

https://huagongshe.com/reaction/15789

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPivaloyl chlorideHCID 62493—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
Product2,2-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)propanamideHCID 4985200366%

Reaction Steps

The title compound was prepared in 66% yield according to the general procedure for the preparation of the amides (Method B) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 2,2-dimethylpropanoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732600B2
Source datasetuspto-grants-2010_06
ORD IDord-fee101fb616c4396be9ed5ffebdd3871
Source noteuspto-grants-2010_06