3-Methoxypropylamine → HCID 21557430, compound

HRID 1578971Notes

Reaction equation

HRID 1578971 reaction equation
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]=1.[CH3:15][O:16][CH2:17][CH2:18][CH2:19][NH2:20]>>[Cl:8][C:6]1[CH:7]=[C:2]([NH:20][CH2:19][CH2:18][CH2:17][O:16][CH3:15])[N:3]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:5]=1

Participants

3

Procedure

In the same manner, 4,6-dichloro-2-phenylpyrimidine is reacted with 3-methoxypropylamine to produce 4-chloro-6-(3-methoxypropylamino)-2-phenylpyrimidine, which is then reacted with p-chlorothiophenol to afford 4-(4-chlorophenylthio)-6-[(3-methoxypropyl)amino]-2-phenylpyrimidine.

Sources & evidence

ORD record
ord-c85a5592068743df96c3ca82ee62af87
Source dataset
uspto-grants-1976_02
Patent number
US03940395

Reaction notes

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