Thiophenol → HCID 131710059, compound

HRID 1578974Notes

Reaction equation

HRID 1578974 reaction equation
Cl[C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]=[C:4]([NH:14][CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])[CH:3]=1.[C:21]1([SH:27])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:8]1([C:6]2[N:5]=[C:4]([NH:14][CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])[CH:3]=[C:2]([S:27][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[N:7]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 7969ThiophenolHCID 115914679HCID 115914679, compound

Product 1

HCID 131710059HCID 131710059, compound

Procedure

A mixture of the above prepared N-(6-chloro-2-phenyl-4-pyrimidinyl)-glycine, ethyl ester is reacted with thiophenol, as in Example X, to afford N-(2-phenyl-6-phenylthio-4-pyrimidinyl)-glycine, ethyl ester.

Workup

  1. additionA mixture of the

Sources & evidence

ORD record
ord-186331460d1942018fcd313bdf73b068
Source dataset
uspto-grants-1976_02
Patent number
US03940395

Reaction notes

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