p-Chlorothiophenol → HCID 21557396, compound

HRID 1578975Notes

Reaction equation

Cl[C:2]1[CH:7]=[C:6]([N:8]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]2)[N:5]=[C:4]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:3]=1.[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([SH:28])=[CH:24][CH:23]=1>>[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([S:28][C:2]2[CH:7]=[C:6]([N:8]3[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]3)[N:5]=[C:4]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[N:3]=2)=[CH:24][CH:23]=1

Participants

Reactant 2

HCID 7815p-Chlorothiophenol

HCID 21557437HCID 21557437, compound

Product 1

HCID 21557396HCID 21557396, compound

Procedure

A mixture of the above prepared 4-chloro-6-(hexahydroazepin-1-yl)-2-phenylpyrimidine is reacted with p-chlorothiophenol, as in Example X, to produce 4-(4-chlorophenylthio)-6-(hexahydroazepin-1-yl)-2-phenylpyrimidine.

Workup

additionA mixture of the

Sources & evidence

ORD record: ord-a1edb154ffb14a389c4f9674604625d3
Source dataset: uspto-grants-1976_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03940395

Reaction notes

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