4-Ethylthiophenol → HCID 21557412, compound
Reaction equation
Cl[C:2]1[CH:7]=[C:6]([NH:8][CH2:9][CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)[N:5]=[C:4]([C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=2)[N:3]=1.[CH2:25]([C:27]1[CH:32]=[CH:31][C:30]([SH:33])=[CH:29][CH:28]=1)[CH3:26]>>[Cl:24][C:21]1[CH:22]=[CH:23][C:18]([C:4]2[N:3]=[C:2]([S:33][C:30]3[CH:31]=[CH:32][C:27]([CH2:25][CH3:26])=[CH:28][CH:29]=3)[CH:7]=[C:6]([NH:8][CH2:9][CH2:10][CH2:11][N:12]3[CH2:17][CH2:16][O:15][CH2:14][CH2:13]3)[N:5]=2)=[CH:19][CH:20]=1Participants
3
Procedure
Similarly, 4-chloro-2-(4-chlorophenyl)-6-[3-(morpholino)propylamino]-pyrimidine is reacted with p-ethylthiophenol to produce 2-(4-chlorophenyl)-4-(4-ethylphenylthio)-6-[3-(morpholino)propylamino]-pyrimidine.
Sources & evidence
- ORD record
- ord-29b67e12439045478d083ccf94c8d127
- Source dataset
- uspto-grants-1976_02
- Patent number
- US03940395
Reaction notes
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