4-ethoxybenzenethiol → HCID 21557392, compound

HRID 1578986Notes

Reaction equation

HRID 1578986 reaction equation
Cl[C:2]1[CH:7]=[C:6]([N:8]2[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][CH2:9]2)[N:5]=[C:4]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)[N:3]=1.[CH2:22]([O:24][C:25]1[CH:30]=[CH:29][C:28]([SH:31])=[CH:27][CH:26]=1)[CH3:23]>>[CH2:22]([O:24][C:25]1[CH:30]=[CH:29][C:28]([S:31][C:2]2[CH:7]=[C:6]([N:8]3[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][CH2:9]3)[N:5]=[C:4]([C:15]3[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=3)[N:3]=2)=[CH:27][CH:26]=1)[CH3:23]

Participants

3

Reactant 2

HCID 91065084-ethoxybenzenethiolHCID 21557455HCID 21557455, compound

Product 1

HCID 21557392HCID 21557392, compound

Procedure

In a similar manner, the above prepared 4-chloro-6-(4-methyl-1-piperazinyl)-2-(4-tolyl)-pyrimidine is reacted with p-ethoxythiophenol to afford 4-(4-ethoxyphenylthio)-6-(4-methyl-1-piperazinyl)-2-(4-tolyl)-pyrimidine.

Sources & evidence

ORD record
ord-011fb74d55984b4097df5940bd524686
Source dataset
uspto-grants-1976_02
Patent number
US03940395

Reaction notes

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