p-Chlorothiophenol → HCID 21557366, compound

Participants

Reaction Steps

Employing the above procedure, 7.0 g. of 4,6-dichloro-2-phenylpyrimidine is reacted with 34 ml. of N,N-diethylethylenediamine, followed by the reaction of the crude product thereof with 12.5 g. of p-chlorothiophenol. Recrystallization of the crude product (3.85 g.) from n-heptane affords 4-(4-chlorophenylthio)-6-[2-(diethylamino)ethylamino]-2-phenylpyrimidine, m.p. 83.5°-86°C.

Provenance & Evidence