反应详情

A 7.4-g (0.45 mole) sample of 1-bromohexane was added at ambient temperature to a stirred solution of 11.1 g (0.05 mole) of tris(dimethylamino)sulfonium thiocyanate in 25 ml acetonitrile, and the rate of the reaction was followed by gas-liquid partition chromatography (glc). The reaction was one-half completed after 3 hr, and was essentially completed after 20 hr. The reaction mixture was poured into water and extracted with ether. The ether extract was dried (MgSO4) and distilled to give 5.47 g (85%) of n-hexyl thiocyanate as a colorless liquid, bp 93°-94° (10 mm).

1. custompartition chromatography (glc)
2. waitwas essentially completed after 20 hr
3. additionThe reaction mixture was poured into water
4. extractionextracted with ether
5. extractionThe ether extract
6. dry with materialwas dried (MgSO4)
7. distillationdistilled