1,4-Dibromobutane → 2-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione

HRID 1579012Notes

Reaction equation

HRID 1579012 reaction equation
Cl.N1C=CC=CC=1N1CCN(CC[CH2:16][CH2:17][N:18]2[C:27](=[O:28])[C:26]3[CH:29]=[CH:30][CH:31]=[C:24]4[C:25]=3[C:20](=[CH:21][CH:22]=[CH:23]4)[C:19]2=[O:32])CC1.[Br:33][CH2:34][CH2:35][CH2:36][CH2:37]CCBr.BrCCCCBr>>[Br:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:16][CH2:17][N:18]1[C:19](=[O:32])[C:20]2[CH:21]=[CH:22][CH:23]=[C:24]3[C:25]=2[C:26](=[CH:29][CH:30]=[CH:31]3)[C:27]1=[O:28]

Participants

4

Reactant 3

HCID 80561,4-DibromobutaneHCID 123681,6-DibromohexaneHCID 1317100602-[4-[4-(2-Pyridinyl)-1-piperazinyl]butyl]-1H-benz[de]-isoquinoline-1,3-(2H)-dione, hydrochloride

Product 1

HCID 203645072-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione

Procedure

Following the procedure of part (a) of example 46 but substituting 1,6-dibromohexane for the 1,4-dibromobutane, one obtains 2-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione; m.p. 95°-96°.

Sources & evidence

ORD record
ord-f8999d200e094963a675d9008b1a316e
Source dataset
uspto-grants-1976_02
Patent number
US03940398

Reaction notes

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