1,4-Dibromobutane → 2-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione

HRID 1579016Notes

Reaction equation

HRID 1579016 reaction equation
Cl.C1(N2CCN(CC[CH2:16][CH2:17][N:18]3[C:27](=[O:28])[C:26]4[CH:29]=[CH:30][CH:31]=[C:24]5[C:25]=4[C:20](=[CH:21][CH:22]=[CH:23]5)[C:19]3=[O:32])CC2)C=CC=CC=1.[Br:33][CH2:34][CH2:35][CH2:36][CH2:37]Br>>[Br:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:16][CH2:17][N:18]1[C:19](=[O:32])[C:20]2[CH:21]=[CH:22][CH:23]=[C:24]3[C:25]=2[C:26](=[CH:29][CH:30]=[CH:31]3)[C:27]1=[O:28]

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 1317100632-[4-(4-Phenyl-1-piperazinyl)butyl]-1H-benz[de]isoquinoline-1,3(2H)-dione, hydrochloride

Product 1

HCID 203645072-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione

Procedure

Following the procedure of part (a) of example 34 but substituting 1,6 -dibromohexane for 1,4-dibromobutane, one obtains 2-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione; m.p. 95°-96°.

Sources & evidence

ORD record
ord-016cbd0e5a1b4b7e9460aff423e24866
Source dataset
uspto-grants-1976_02
Patent number
US03940397

Reaction notes

Loading…