1,4-Dibromobutane → 2-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

HRID 1579018Notes

Reaction equation

HRID 1579018 reaction equation
Cl.C1(N2CCN([CH2:14][CH2:15][CH2:16][CH2:17][N:18]3[C:27](=[O:28])[C:26]4[CH:29]=[CH:30][CH:31]=[C:24]5[C:25]=4[C:20](=[CH:21][CH:22]=[CH:23]5)[C:19]3=[O:32])CC2)C=CC=CC=1.[Br:33][CH2:34]CCCCBr.BrCCCCBr>>[Br:33][CH2:34][CH2:14][CH2:15][CH2:16][CH2:17][N:18]1[C:27](=[O:28])[C:26]2[CH:29]=[CH:30][CH:31]=[C:24]3[C:25]=2[C:20](=[CH:21][CH:22]=[CH:23]3)[C:19]1=[O:32]

Participants

4

Reactant 3

HCID 80561,4-DibromobutaneHCID 81001,5-DibromopentaneHCID 1317100632-[4-(4-Phenyl-1-piperazinyl)butyl]-1H-benz[de]isoquinoline-1,3(2H)-dione, hydrochloride

Product 1

HCID 166387912-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

Procedure

Following the procedure of part (a) of example 34 but substituting 1,5-dibromopentane for the 1,4-dibromobutane, one obtains 2-(5-bromopentyl)-1H-benz[de]isoquinoline-1,3(2H)-dione; m.p. 113°-115°.

Sources & evidence

ORD record
ord-dfd5740374e64f25a9d98531f2cc8bc1
Source dataset
uspto-grants-1976_02
Patent number
US03940397

Reaction notes

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