1,2-Dihydro-9-hydroxy-7-(3-methyl-2-octyl)-4-oxo-4H-thieno[2,3-c][1]benzopyran → 4,4-di(1-hexyl)-1,2-dihydro-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno[2,3-c][1]benzopyran

HRID 1579094Notes

Reaction equation

HRID 1579094 reaction equation
[OH:1][C:2]1[C:7]2[C:8]3[CH2:15][CH2:14][S:13][C:9]=3[C:10](=O)[O:11][C:6]=2[CH:5]=[C:4]([CH:16]([CH:18]([CH3:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH3:17])[CH:3]=1.[CH2:25]([Mg]Br)[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>>[CH2:25]([C:10]1([CH2:6][CH2:7][CH2:2][CH2:3][CH2:4][CH3:5])[C:9]2[S:13][CH2:14][CH2:15][C:8]=2[C:7]2[C:2]([OH:1])=[CH:3][C:4]([CH:16]([CH:18]([CH3:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH3:17])=[CH:5][C:6]=2[O:11]1)[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]

Participants

3

Reactant 2

HCID 214339001,2-Dihydro-9-hydroxy-7-(3-methyl-2-octyl)-4-oxo-4H-thieno[2,3-c][1]benzopyranHCID 178444609HCID 178444609, compound

Product 1

HCID 215579124,4-di(1-hexyl)-1,2-dihydro-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno[2,3-c][1]benzopyran

Procedure

By reacting 1,2-dihydro-9-hydroxy-7-(3-methyl-2-octyl)-4-oxo-4H-thieno[2,3-c][1]benzopyran with n-hexylmagnesium bromide, using the manipulative procedure described in Example 8, there is obtained 4,4-di(1-hexyl)-1,2-dihydro-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno[2,3-c][1]benzopyran.

Sources & evidence

ORD record
ord-e6bc6bf7bd9540c88ed6e3f56f793cdf
Source dataset
uspto-grants-1976_02
Patent number
US03940421

Reaction notes

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