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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 157915Generated: November 2, 2026

1,4-Dioxane → 1-(5-[2-[(2-Dimethylamino-ethyl)-methyl-amino]-6-methyl-pyrimidin-4-yl]-4-methyl-thiazol-2-yl)-3-[2-(1-ethyl-1H-imidazol-4-yl)-ethyl]-urea

https://huagongshe.com/reaction/157915

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
Reactant1,2-Ethanediamine, N1,N1,N2-trimethyl-HCID 67338—
Reactant1-[2-(1-Ethyl-1H-imidazol-4-yl)-ethyl]-3-[5-(2-methanesulfinyl-6-methyl-pyrimidin-4-yl)-4-methyl-thiazol-2-yl]-ureaHCID 11166394—
Product1-(5-[2-[(2-Dimethylamino-ethyl)-methyl-amino]-6-methyl-pyrimidin-4-yl]-4-methyl-thiazol-2-yl)-3-[2-(1-ethyl-1H-imidazol-4-yl)-ethyl]-ureaHCID 86653062—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-e1da6f3d7ea24c4ebb41db3c6bb393db
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)