Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | α-(1-Methylethyl)-2-pyridineethanethioamide | HCID 15581943 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 15581944 | HCID 15581944 | — |
Reaction Steps
To a solution of 1.0 g. of 3-methyl-2-(2-pyridyl)thiobutanamide in 20 ml. of methanol is added, at one time, 0.45 g. of morpholine and 0.42 ml. of a 37 percent formalin solution. The reaction is stirred for 15 hours at 25°C., then refluxed on a steam bath for 20 minutes. The solvents are evaporated in vacuo and the residue is distilled to give 3-methyl-N-morpholinomethyl-2-(2-pyridyl)thiobutanamide, b.p. 110-+-112°C. (0.005 mm.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03931162 |
|---|
| Source dataset | uspto-grants-1976_01 |
|---|
| ORD ID | ord-27fe8e24f30444bfa34e6598f7a05df0 |
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| Source note | uspto-grants-1976_01 |
|---|
