Formaldehyde → HCID 21566927, compound

HRID 1579200Notes

Reaction equation

HRID 1579200 reaction equation
[CH2:1]([CH:8]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=1)[C:9]([NH2:11])=[S:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:18]1[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1.[CH2:24]=O>>[CH2:1]([CH:8]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=1)[C:9]([NH:11][CH2:24][N:18]1[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1)=[S:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 712FormaldehydeHCID 8083MorpholineHCID 21547247HCID 21547247, compound

Product 1

HCID 21566927HCID 21566927, compound

Procedure

By the procedure of Example 14, 2-benzyl-2-(2-pyridyl)thioacetamide is reacted with morpholine and formaldehyde to give 2-benzyl-N-morpholinomethyl-2-(2-pyridyl)thioacetamide.

Sources & evidence

ORD record
ord-75d9d7d0e0564c4388581a501b686c56
Source dataset
uspto-grants-1976_01
Patent number
US03931162

Reaction notes

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