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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 157922Generated: October 26, 2026

Tetrahydrofuran → 5-Amino-N-[2-({[(2,6-dichlorophenyl)carbonyl]amino}methyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide

https://huagongshe.com/reaction/157922

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2,6-Dichlorobenzoyl chlorideHCID 78392—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-amino-N-[2-(aminomethyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamideHCID 59487494—
Product5-Amino-N-[2-({[(2,6-dichlorophenyl)carbonyl]amino}methyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamideHCID 23649465—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-c049218610384a338b57b612652d8cd1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)