Methanol → Methyl 2,10-dimethyl-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate

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Reaction Steps

The carboxylic acid was dissolved in 300 ml of methanol and 2 ml of concentrated sulfuric acid was added. The mixture was refluxed for 1 hour, cooled, the resulting crystals collected and recrystallized from methanol-acetone to give methyl 2,10-dimethyl-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate, m.p. 158°-160°C. The methyl ester and excess diethylamine are refluxed for 16 hours. The remaining diethylamine is removed, and N,N-diethyl-2,10-dimethyl-12H-dibenzo[d,g][1,3]dioxocin-6-carboxamide is obtained.

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