HCID 178477676, compound → HCID 178477677, compound

HRID 1579224Notes

Reaction equation

HRID 1579224 reaction equation
[CH2:1]([S:3]([CH2:6][C:7]1[C:16](C(OC)=O)=[N+:15]([O-:21])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[N+:8]=1[O-:22])(=[O:5])=[O:4])[CH3:2]>[OH-].[Na+]>[CH2:1]([S:3]([CH2:6][C:7]1[CH:16]=[N+:15]([O-:21])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[N+:8]=1[O-:22])(=[O:5])=[O:4])[CH3:2]

Participants

3

Reactant 1

HCID 178477676HCID 178477676, compound

Product 1

HCID 178477677HCID 178477677, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Conditions

Temperature
120 °C

Procedure

A slurry of 2-ethylsulfonylmethyl-3-carbomethoxyquinoxaline-1,4-dioxide (28.2 g., 0.087 m) and 0.5 N sodium hydroxide (280 ml.) was stirred at room temperature for 30 minutes. It was then filtered and the filtrate acidified to pH 3 with 6N hydrochloric acid. The resulting slurry was heated in an oil bath (bath temperature 120°C.) for 30 minutes. It was removed from the oil bath, allowed to cool to room temperature and the solid filtered off: 22.2 g. (95 percent yield); m.p. 216°C.

Workup

  1. filtrationIt was then filtered
  2. customIt was removed from the oil bath
  3. temperatureto cool to room temperature
  4. filtrationthe solid filtered off

Sources & evidence

ORD record
ord-9ee560345b864bb38e5d341a6fc836f9
Source dataset
uspto-grants-1976_01
Patent number
US03931174

Reaction notes

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