HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → HCID 21450221, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | HCID 21450252 | HCID 21450252 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 21450221 | HCID 21450221 | 97.9% |
Reaction Steps
A mixture of 3-[4-(2,3-epoxypropoxy)benzoyl]-N-methylpropionamide (20 g, 0.076 mole), methanol (200 ml) and isopropylamine (36 ml, 0.42 mole) was heated under reflux for 1 hour. Evaporation under reduced pressure gave 3-[4-(2-hydroxy-3-isopropylaminopropoxy)benzoyl]-N-methylpropionamide (24 g, 97%, m.p. 139°-142°C). Crystallisation from water gave the pure amide, m.p. 140°-142°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03931177 |
| Source dataset | uspto-grants-1976_01 |
| ORD ID | ord-a049f8970db84096936cbda14861096c |
| Source note | uspto-grants-1976_01 |