Sodium Carbonate → HCID 21450269, compound

Participants

Reaction Conditions

Reaction Steps

4-Bromo-2-bis(2-hydroxyethyl)aminophenol (2.5 g) was dissolved in 70% sulphuric acid (25 ml) and the solution heated to 160°C for 3 hours, allowed to cool, then neutralised with saturated sodium carbonate solution. Extraction with ether and evaporation of the extracts gave crude 4-bromo-2-morpholinophenol which was crystallised from ether gave the pure phenol (1.4 g, 60%, m.p. 128°C).

Provenance & Evidence