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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1579289Generated: November 3, 2026

Boron tribromide → Ethyl 3,4-dihydroxy-γ-oxobenzenebutanoate

https://huagongshe.com/reaction/1579289

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoron tribromideHCID 25134—
ReactantEthyl 4-(3,4-dimethoxyphenyl)-4-oxobutanoateHCID 249925—
SolventDichloromethaneHCID 6344—
ProductEthyl 3,4-dihydroxy-γ-oxobenzenebutanoateHCID 11253386—

Reaction Steps

Ethyl 3-(3,4-dimethoxybenzoyl)propionate was demethylated with boron tribromide in dichloromethane at -80°C to give ethyl 3-(3,4-dihydroxybenzoyl)propionate, m.p. 116°-117°C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03931177
Source datasetuspto-grants-1976_01
ORD IDord-3e898f75e2d64b99ba982e5264afafda
Source noteuspto-grants-1976_01