HCID 21568305, compound → HCID 21568302, compound

Participants

Reaction Steps

This compound was prepared from 1-hydroxy-phosphindoline 1-oxide (3.0g, 17.9 mmol) by a method similar to that used for the preparation of 1-ethyl-1,2,3,4-tetrahydrophosphinoline 1-oxide described above, except that anhydrous tetrahydrofuran was used as solvent. Isolation with chloroform and bulb to bulb distillation of the residue at 160°/0,1 mm gave a colourless hygroscopic liquid (2.3 g, 72%). Preparative T.l.c. (RF 0.38, chloroform/methanol 15:1), and bulb to bulb distillation of the major component gave "pure" 1-ethylphosphindoline-1-oxide as a colourless hygroscopic liquid. This was shown to be pure by g.l.c.

Provenance & Evidence